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EFFECTS OF TRANSPORT STRESS ON THE INTESTINES INVOLVING NEURONAL NITRIC OXIDE SYNTHASE
《农业科学与工程前沿(英文)》 页码 285-295 doi: 10.15302/J-FASE-2022469
● Transport stress declined the level of leukocytes including lymphocytes in rat serum.
Protective roles of heat stress on the neurons in hippocampal CA1 region of mice
WANG Chunxu, WANG Hanxing
《医学前沿(英文)》 2007年 第1卷 第4期 页码 418-422 doi: 10.1007/s11684-007-0082-7
Lei FU MD , Dezheng GONG BM , Yan PENG , Dongmei WANG BM , Hong XU , Yue LI MD , Dengqin YU BS , Yanhui FENG MD , Shengming YIN PhD , Jin GONG , Yiping SUN PhD ,
《医学前沿(英文)》 2009年 第3卷 第3期 页码 330-335 doi: 10.1007/s11684-009-0051-4
关键词: Parkinson disease nicotine dopaminergic neuron gamma-aminobutyric acid neuron
null
《医学前沿(英文)》 2017年 第11卷 第2期 页码 223-228 doi: 10.1007/s11684-017-0517-8
The objective of this study is to guide a triage for the management of cervical high-grade squamous intraepithelial lesion (HSIL) patients with positive margin by conization. Clinico-pathological data of HSIL patients with positive margin by conization were retrospectively collected from January 2009 to December 2014. All patients underwent secondary conization or hysterectomy within 6 months. The rate of residual lesion was calculated, and the factors associated with residual lesion were analyzed by univariate and multivariate analyses. Among a total of 119 patients, 56 (47.06%) patients presented residual HSIL in their subsequent surgical specimens, including 4 cases of invasive cervical carcinoma (3 stage IA1 and 1 stage IA2 patients). Univariate analysis showed that patient age>35 years (P=0.005), menopausal period>5 years (P=0.0035), and multiple-quadrant involvement (P=0.001) were significantly correlated with residual disease; however, multivariate analysis revealed that multiple-quadrant involvement (P=0.001; OR, 3.701; 95%CI, 1.496–9.154) was an independent risk factor for residual disease. Nearly half of HSIL patients with positive margin by conization were disease-free in subsequent surgical specimens, and those with multiple positive margins may consider re-conization or re-assessment.
关键词: cervical high-grade squamous intraepithelial lesion conization positive surgical margin hysterectomy
NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions
HE Wei, ZHU Tianle, LI Jing
《环境科学与工程前沿(英文)》 2007年 第1卷 第2期 页码 153-158 doi: 10.1007/s11783-007-0027-z
关键词: conversion streamer discharge wheel-cylinder positive streamer
XIA Jiao, KONG Weijia, ZHU Yun, ZHOU Yan, ZHANG Yu, GUO Changkai
《医学前沿(英文)》 2008年 第2卷 第3期 页码 264-268 doi: 10.1007/s11684-008-0050-x
关键词: resistance infrared infrared videomicroscopy depressive after-hyperpolarization potential
甘自恒
《中国工程科学》 2007年 第9卷 第2期 页码 5-11
据预测,2020年,全球将进入以生物技术产业为主导产业的生物经济时代;阐述了生物经济的提出、 分类、特征和定义;主张把握生物经济时代精神,实践进步的幸福观;探讨了为什么要强调谋求人民幸福,什 么是进步的幸福观,应提倡那些进步的幸福观,以及我国科技界应该怎样实践进步的幸福观。
Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breast
Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen
《医学前沿(英文)》 2021年 第15卷 第4期 页码 621-628 doi: 10.1007/s11684-020-0738-0
关键词: early breast cancer 21-gene assay recurrence score prognosis
GID complex regulates the differentiation of neural stem cells by destabilizing TET2
《医学前沿(英文)》 doi: 10.1007/s11684-023-1007-9
关键词: TET2 GID complex neural stem cells differentiation of neurons
null
《医学前沿(英文)》 2017年 第11卷 第3期 页码 440-444 doi: 10.1007/s11684-017-0523-x
Philadelphia chromosome-positive acute myeloid leukemia is controversial and difficult to distinguish from the blast phase of chronic myeloid leukemia. As a myeloid neoplasm, rare cases of this leukemia manifest multiple soft-tissue tumors or bone lytic lesions. In this paper, we describe a 49-year-old male patient who had an abrupt onset with sharp chest pain, fever, fatigue, emaciation, and splenomegaly. 18F-fluoro-deoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) result showed diffuse and uneven hypermetabolic lesions in the bone marrow with peripheral bone marrow expansion, multiple soft tissue neoplasms with high 18F-FDG uptake, and lytic bone lesions. Bone marrow smear and biopsy detected aberrant blast cells expressing myeloid rather than lymphoid immunophenotype marker. For the existence of Philadelphia chromosome and BCR-ABL1 fusion gene together with complex chromosome abnormalities, a diagnosis of Philadelphia-positive acute myeloid leukemia was made, although the type (de novo or blast crisis) remained unclear.
关键词: Philadelphia chromosome acute myeloid leukemia mass osteolysis positron emission tomography
null
《医学前沿(英文)》 2017年 第11卷 第2期 页码 229-238 doi: 10.1007/s11684-017-0506-y
A CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group for adult acute lymphoblastic leukemia (ALL). We retrospectively analyzed 153 newly diagnosed adult patients with Philadelphia chromosome (Ph)-positive ALL enrolled into imatinib (400 mg/d) plus CALLG2008 regimen between 2009 and 2015. The median age was 40 years (range, 18–68 years), with 81 (52.3%) males. The overall hematologic complete remission (CR) rate was 96.7% after induction. With a median follow-up of 24.2 months, the estimated 3-year overall survival (OS) and event-free survival (EFS) rates were 49.5% (95% confidence interval (CI): 38.5%–59.5%) and 49.2% (95% CI: 38.3%–59.2%), respectively. Fifty-eight (36 with haploidentical donor) patients underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) in first CR. Among the patients in CR1 after induction, both the 3-year OS and EFS were significantly better in the allo-HSCT group than in the without allo-HSCT group (73.2%, 95% CI: 58.3%–83.5% vs. 22.2%, 95% CI: 8.7%–39.6% and 66.5%, 95% CI: 50.7%–78.2% vs. 16.1%, 95% CI: 5.1%–32.7%, respectively). Multivariate analysis showed that allo-HSCT and achievement of major molecular response were associated with favorable OS or EFS independently. Interestingly, in the allo-HSCT cohort, the donor type (haploidentical versus matched donors) had no significant impact on EFS or OS. All these results suggested that imatinib plus CALLG2008 was an effective protocol for Ph-positive ALL. Haploidentical donors can also be a reasonable alternative expedient donor pool.
关键词: Philadelphia chromosome acute lymphoblastic leukemia imatinib CALLG2008
Wenjie Zhu, Binghe Xu
《医学前沿(英文)》 2021年 第15卷 第2期 页码 208-220 doi: 10.1007/s11684-020-0795-4
关键词: endocrine-resistant HR+/HER2- advanced breast cancer randomized clinical trials meta-analysis targeted therapy
神经元之间的相位同步和能量平衡 Research Article
谢盈1,姚昭1,马军1,2
《信息与电子工程前沿(英文)》 2022年 第23卷 第9期 页码 1407-1420 doi: 10.1631/FITEE.2100563
N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes
Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin
《化学科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 64-71 doi: 10.1007/s11705-021-2048-8
关键词: heterocyclic compound hydrogen sulfide ratiometric mitochondrial targeted
Fernando F. Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas
《化学科学与工程前沿(英文)》 2021年 第15卷 第2期 页码 399-409 doi: 10.1007/s11705-020-1934-9
关键词: CFD simulation porous media porous electrode pressure drop redox flow battery
标题 作者 时间 类型 操作
Protective roles of heat stress on the neurons in hippocampal CA1 region of mice
WANG Chunxu, WANG Hanxing
期刊论文
Protective effects of nicotine on gamma-aminobutyric acid neurons and dopaminergic neurons in mice with
Lei FU MD , Dezheng GONG BM , Yan PENG , Dongmei WANG BM , Hong XU , Yue LI MD , Dengqin YU BS , Yanhui FENG MD , Shengming YIN PhD , Jin GONG , Yiping SUN PhD ,
期刊论文
Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin
null
期刊论文
NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions
HE Wei, ZHU Tianle, LI Jing
期刊论文
Spontaneous firing properties of rat medial vestibular nucleus neurons in brain slices by infrared visual
XIA Jiao, KONG Weijia, ZHU Yun, ZHOU Yan, ZHANG Yu, GUO Changkai
期刊论文
Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breast
Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen
期刊论文
Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of
null
期刊论文
of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed Philadelphia chromosome-positive
null
期刊论文
Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor
Wenjie Zhu, Binghe Xu
期刊论文
N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes
Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin
期刊论文